Compound library / Longevity / Anti-aging

GDF-11 (Growth Differentiation Factor 11)

TGF-β superfamily member initially acclaimed in parabiosis studies as a "rejuvenating" factor that declines with age; subsequent research has produced conflicting results regarding its age-reversal effects. Explored for muscle, cardiac, and neurological regeneration.

CategoryLongevity / Anti-aging
Regulatory standingNo approved product cited
Typical routeSubcutaneous
Half-lifeNot well characterized in humans
Common dose rangeResearch-stage only — no established human dosing
Typical cycle lengthNot established

BioHack Track models GDF-11 (Growth Differentiation Factor 11) at a half-life of 2 hours, so every dose you log is decayed against that curve and the app shows estimated active levels — not just what you typed.

No approved product cited

No FDA-approved product for this compound is cited on this page, and no approved human dose is quoted. Treat the range below as research and community practice rather than a prescribed dose.

Reconstitution

Reconstitute with bacteriostatic water or PBS per supplier guidance; requires careful handling.

Storage

Refrigerate or freeze as directed; highly sensitive to repeated freeze-thaw cycles.

Cautions

Conflicting preclinical data — some studies show benefits, others show cardiac fibrosis or no effect. No human clinical trials to date; safety profile entirely unknown in people.

Track GDF-11 (Growth Differentiation Factor 11) in BioHack Track. Half-life, dose range and route come pre-filled from this library — log a dose and the app counts your vial down, models what is in your system, and puts it on the same chart as your labs and body composition.

Others in Longevity / Anti-aging

Look up the research

These open a search of each database for GDF-11 (Growth Differentiation Factor 11) — they are not citations, and nothing here is evidence for any particular dose. The same links are in the app.

Work it out

Where these figures come from

The half-life, route and dose range on this page are compiled from published pharmacokinetic literature, manufacturer and product monographs where one exists, and the ranges commonly reported in clinical and research use. They are kept as a range rather than a single figure because that is what the sources actually support — a half-life varies with route, formulation and the person.

These are not citations, and this page is not a review of the evidence. Where a number matters to you, follow the database links above and read the source. We say so plainly rather than dressing a compiled reference up as one.

Nothing on this page has been reviewed by a named clinician. It is a reference for people already tracking a protocol, not a recommendation to start one.

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