Compound library / Longevity / Anti-aging
mTOR complex 1 (mTORC1) inhibitor that extends lifespan in multiple organisms, including mice. The most pharmacologically well-characterized longevity compound. Used clinically as an immunosuppressant after organ transplant; explored off-label in low intermittent doses for aging.
| Category | Longevity / Anti-aging |
|---|---|
| Regulatory standing | Approved medicine |
| Typical route | Oral |
| Half-life | ~62 hours |
| Common dose range | Organ transplant: 2-5 mg/day. Off-label longevity protocols: 1-6 mg/week or biweekly (highly variable and not standardized) |
| Typical cycle length | Ongoing or pulsed protocols; not established for longevity use |
BioHack Track models Rapamycin (Sirolimus) at a half-life of 62 hours, so every dose you log is decayed against that curve and the app shows estimated active levels — not just what you typed.
An FDA-approved product containing this compound exists, and its label is linked under Primary sources below. That label is the authority on dosing; the range on this page describes what people commonly track, including off-label use, and does not replace it.
Oral tablet or liquid; no reconstitution needed.
Store at room temperature; liquid formulation must be refrigerated after opening.
Prescription medication (immunosuppressant). Even low intermittent doses carry real immune-suppression risk, impair wound healing, and can raise lipids and blood glucose. Requires physician supervision and monitoring.
Track Rapamycin (Sirolimus) in BioHack Track. Half-life, dose range and route come pre-filled from this library — log a dose and the app counts your vial down, models what is in your system, and puts it on the same chart as your labs and body composition.
These open a search of each database for Rapamycin (Sirolimus) — they are not citations, and nothing here is evidence for any particular dose. The same links are in the app.
Primary sources for Rapamycin (Sirolimus)
The half-life, route and dose range on this page are compiled from published pharmacokinetic literature, manufacturer and product monographs where one exists, and the ranges commonly reported in clinical and research use. They are kept as a range rather than a single figure because that is what the sources actually support — a half-life varies with route, formulation and the person.
These are not citations, and this page is not a review of the evidence. Where a number matters to you, follow the database links above and read the source. We say so plainly rather than dressing a compiled reference up as one.
Nothing on this page has been reviewed by a named clinician. It is a reference for people already tracking a protocol, not a recommendation to start one.
General reference compiled for use inside the app, not medical advice and not a recommendation to take anything. Dose ranges are what is commonly discussed, not a prescription. Talk to a qualified healthcare professional.